Environmental Biotechnology:

Advanced wastewater treatment and reuse effluents desalination biofouling removal and degradation of micropollutants membrane bioreactors biofilters

Brief Biography

Graduated in Chemical Engineering (Universidad del Litoral, Argentina) and PhD degree in Biotechnology (Department of Biotechnology of Tel Aviv University, Israel) and Postdoc in the Department of Chemical Engineering at Michigan State University, East Lansing (USA). Joined the Faculty of Civil and Environmental Engineering at the Technion, Haifa (Israel) in 2000, following 10 years of research and education in Environmental Biotechnology at Migal Research Institute/Tel Hai Academic College (Upper Galilee, Israel). Visiting/Guest Professor in the Department of Civil and Environmental Engineering at the University of California at Davis, USA (2006-2007), Department of Chemical Engineering at the University of Barcelona, Spain (2016), Graduate School of Global Environmental Studies at Kyoto University, Japan and Faculty of Engineering and Information Technology at University of Technology Sydney, Australia (2019).

Authored/co-authored above140 peer-reviewed research papers, review papers and books chapters and has 5 patents. Supervision of 50 graduate students (15 PhD and 35 MSc). Awarded the Shilo Prize in Environmental Microbiology by the Israeli Society for Microbiology in 2003. Editorial board of Bioresource Technology and Environment International (Elsevier). Member/head in different scientific and public boards, steering committees, review panels and professional societies and conferences organization and former Head of the Division of Environmental, Water and Agricultural Engineering at the Faculty of Civil and Environmental Engineering, Technion.

Selected refereed papers in scientific journals

  1. Dosoretz, C.G., H.C. Chen, and H.E. Grethlein. Effect of environmental conditions on extracellular protease activity in lignolytic cultures of Phanerochaete chrysosporium. Appl. Environ. Microbiol. 56: 395‑400, 1990.
  2. Dosoretz, C.G., S.B. Dass, C.A. Reddy, and H.E. Grethlein. Protease mediated degradation of lignin peroxidase in liquid cultures of Phanerochaete chrysosporium. Appl. Environ. Microbiol. 56: 3429-3434, 1990.
  3. Dosoretz, C.G., N. Rothschild, and Y. Hadar. Overproduction of the ligninolytic system of Phanerochaete chrysosporium (BKM-F) under non-limiting nutrient conditions. Appl. Environ. Microbiol. 59: 1919-1926, 1993.
  4. Belinki, P., S. Masaphy, D. Levanon, Y. Hadar, and C.G. Dosoretz. Effect of medium composition on 1-octen-3-ol formation in submerged cultures of Pleurotus pulmonarius. Appl. Microbiol. Biotechnol. 40: 629-633, 1994.
  5. Rothschild, N., Y. Hadar, and C.G. Dosoretz.  Ligninolytic system formation by Phanerochaete chrysosporium in air. Appl. Environ. Microbiol. 61:1833-1838, 1995.
  6. Assaf S., Y. Hadar, and C.G. Dosoretz.  Biosynthesis of 13-hydroperoxilinoleate, 10-oxo-8-decenoic acid and 1-octen-3-ol from linoleic acid by a mycelial pellet homogenate of Pleurotus pulmonarius. J. Argic. Food Chem. 43:2173-2178, 1995.
  7. Dosoretz, C.G., R. Armon, J. Starosvetzky, and N. Rothschild. Entrapment of parathion hydrolase from Pseudomonas sp. in sol-gel glass. J. Sol-Gel Sci. Technol. 7:7-11, 1996.
  8. Rothschild, N., Y. Hadar, and C.G. Dosoretz. Lignin peroxidase isozymes from Phanerochaete chrysosporium can be enzymatically dephosphorylated. Appl. Environ. Microbiol. 63: 857-861, 1997.
  9. Rothschild, N., A. Levkowitz, Y. Hadar, and C.G. Dosoretz. Manganese deficiency can replace high oxygen level needed to induce lignin peroxidase formation by Phanerochaete chrysosporium. Appl. Environ. Microbiol. 65:483-488, 1999.
  10. Mason, C.A., G. Ward, K. Abu-Saleh, O. Keren, and C.G. Dosoretz.  Biodegradation of BTEX by bacteria on powdered activated carbon. Bioproc. Eng. 23: 331-336, 2000.
  11. Katz, I., Y. Ruskiol, M. Green, and C.G. Dosoretz. Characterization of atrazine degradation and nitrate reduction by Pseudomonas sp. Strain ADP. Adv. Environ. Res. 4: 219-224, 2000.
  12. Ward, G., Y. Hadar, I. Bilkis, L. Konstantinovsky and C.G. Dosoretz.  Initial steps of ferulic acid polymerization by lignin peroxidase. J. Biol. Chem. 276:18734-18741, 2001.
  13. Degani, O., S. Gepstein, S., and C.G. Dosoretz. The potential use of cutinase in enzymatic scouring of the cotton fiber cuticle. Appl. Biochem. Biotechnol. 102: 277-89, 2002.
  14. Levy, I., G. Ward, Y. Hadar, O. Shoseyov, and C.G. Dosoretz. Oxidation of 4-bromophenol by the recombinant fused protein cellulose-binding domain-horseradish peroxidase immobilized on cellulose. Biotechnol. Bioeng. 82: 223-231, 2003.
  15. Ward, G., Y. Hadar, I. Bilkis, and C.G. Dosoretz. Mechanistic features of lignin peroxidase catalyzed oxidation of substituted phenols and 1,2-dimethoxyarenes. J. Biol. Chem. 278: 39726–39734, 2003.
  16. Belinky, P.A., N. Flikshtein, S. Lechenko, S. Gepstein, and C.G. Dosoretz. Reactive oxygen species and induction of lignin peroxidase in Phanerochaete chrysosporium. Appl. Environ. Microbiol. 69: 6500-6506, 2003.
  17. Ward, G., Y. Hadar, and C.G. Dosoretz. Lignin peroxidase-catalyzed polymerization and detoxification of toxic halogenated phenols. J. Chem. Technol. Biotechnol. 78:1239-1245, 2003.
  18. Dosoretz, C.G. and K.W. Böddeker. Removal of trace organics from water using a pumped bed-membrane bioreactor with powdered activated carbon. J. Membrane Sci. 239: 81-90, 2004.
  19. Ward, G., R. Parales and C.G. Dosoretz. Biocatalytic synthesis of polycatechols from toxic aromatic compounds. Environ. Sci. Technol. 38:4753-4757, 2004.
  20. Ramon, G., M. Green, R. Semiat, and C.G. Dosoretz. Low strength graywater characterization and treatment by direct membrane filtration. Desalination. 170:241-250, 2004.
  21. Ivnitsky H., I. Katz, D. Minz, E. Shimoni, Y. Chen, J. Tarchitzky, R. Semiat and C.G. Dosoretz. Characterization of membrane biofouling in nanofiltration processes of wastewater treatment. Desalination 185:255–268, 2005.
  22. Geffen N., R. Semiat, M.S. Eisen, Y. Balazs, I. Katz and C.G. Dosoretz. Boron removal from water by complexation to polyol compounds. J. Membrane Sci. 286:45-51, 2006.
  23. Ivnitsky H., I. Katz, D. Minz, G. Volvovic, E. Shimoni, E. Kesselman, R. Semiat and C.G. Dosoretz. Bacterial community composition and structure of biofilms developing on nanofiltration membranes applied to wastewater treatment. Water Res.  41:3924-3935, 2007.
  24. Gur-Reznik S., I. Katz and C.G. Dosoretz. Removal of dissolved organic matter by granular activated carbon adsorption as a pretreatment to reverse osmosis-desalination of membrane bioreactor effluents. Water Res. 42:1595-1605, 2008.
  25. Eshed L., S. Yaron and C.G. Dosoretz. The effect of cross-flow on the development of the biofouling layer on pressure driven-membrane separation systems. Appl. Environ. Microbiol. 74:7338–7347, 2008.
  26. Lew B., S. Tarre, M. Beliavski, C.G. Dosoretz and M. Green. Anaerobic membrane bioreactor (AnMBR) for domestic wastewater treatment. Desalination 243:251–257, 2009.
  27. Ramon, G., Y. Agnon and C.G Dosoretz. Dynamics of an osmotic backwash cycle. J Membrane Sci. 364:157-166, 2010.
  28. Berman T., R. Mizrahi and C.G. Dosoretz. Transparent exopolymer particles (TEP): a critical factor in aquatic biofilm initiation and fouling on filtration membranes. Desalination 276:184–190, 2011.
  29. Gur-Reznik S., S.P. Azerrad, Y. Levinson, Heller-Grossman and C.G. Dosoretz. Iodinated contrast media oxidation by nonthermal plasma: the role of iodine as a tracer. Water Res. 45:5047-5057, 2011.
  30. Ramon G.Z., Y. Naaman and C.G. Dosoretz. Engineered osmosis for pre-concentration of sugar-derived biofuels. RSC Adv. 3, 11467-11471, 2013.
  31. Ronen A., R. Semiat and C.G. Dosoretz. Impact of ZnO embedded feed spacer on biofilm development in membrane systems. Water Res. 47:6628-6638, 2013.
  32. Azerrad S.P., S. Gur-Reznik, L. Heller-Grossman and C.G. Dosoretz. Advanced oxidation of iodinated X-ray contrast media in reverse osmosis brines: The influence of quenching. Water Res. 62:107-116, 2014.
  33. Dawas A., S. Gur-Reznik, S. Lerman, I. Sabbah and C.G. Dosoretz. Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment. Bioresour. Technol. 167:336-342, 2014.
  34. Ronen A., S. Lerman, G.Z. Ramon and C.G. Dosoretz. Experimental characterization and numerical simulation of the antibiofuling activity of nanosilver-modified feed spacers in membrane filtration. J. Membr. Sci. 475:320–329, 2015.
  35. Kartashevsky M., R. Semiat and C.G. Dosoretz. Phosphate adsorption on granular ferric hydroxide to increase product water recovery in reverse osmosis-desalination of secondary effluents. Desalination 364:53–61, 2015.


Selected refereed review papers and invited chapters in books

  • Dosoretz, C.G, R. Mandelbaum, and Y. Hadar. Compost; Biodegradation of toxic organic compounds. In G. Bitton (ed.), Encyclopedia of Environmental Microbiology, John Wiley & Sons, New York, pp. 914-927, 2002.
  • Dosoretz, C.G, and G. Ward. Peroxidases. In A. Pandey, C. Webb, C.R. Soccol and C. Larroche (eds.), Enzyme Technology, Springer Science, USA, pp. 399-432, 2005.
  • Dosoretz C.G. and C.A. Reddy.  Lignin and lignin-modifying enzymes. In C.A. Reddy, T.J. Beveridge, J.A. Breznak, G. Marzluf, T.M. Schmidt and L.R. Snyder (eds.), Methods for General and Molecular Microbiology, 3rd Edition, ASM Press, Washington, DC, USA, Chapter 25, pp. 611-620, 2007.
  • Dosoretz C.G., J. Tarchitzky, I. Katz, E. Kenig and Y. Chen. Fouling in microirrigation systems applying treated wastewater effluents. In G. Levy, P. Fine and A. Bar-Tal (eds.), Treated Wastewater in Agriculture: Use and impacts on the soil environments and crops, Wiley-Blackwell, Oxford, U.K., Chapter 10, pp. 328-350, 2010.
  • Gur-Reznik S. and C.G. Dosoretz. Viability and reliability of dense membranes in removing trace organic contaminants for wastewater reclamation and purification: pros and cons, mechanisms, and trends. In R. Armon and O. Hänninen (eds.), Environmental Indicators, Springer, Chapter 45, pp. 805-823, 2015.


  1. Belinky P., H. Lasser and C.G. Dosoretz. Methods of producing lignin peroxidase and its use in skin and hair lightening. WO 2004/052654, 2004; US 12153880, 2008.
  2. Belinky P., H. Lasser and C.G. Dosoretz. Use of lignin peroxidase in skin and hair lightening, EP 1583512, 2011.
  3. Agnon Y., G. Ramon and C.G. Dosoretz. System and method for energy conversion by pressure wave and/or phase-exchange. WO 2012/011096, 2012; US 9,562,522, 2017.
  4. Dosoretz C.G, A. Ronen and R. Semiat. Filtration module. US 15214649, 2016.
  5. Dosoretz C.G, A. Ronen, C. Thamaraiselvan and S. Lerman Toyblat. Carbon nanotube laminates. US 2018/0237301A1, 2018.